Yes. Using Adrenaline (a PSP emulator for the Vita), the School Days ISO PSP English High Quality runs flawlessly. Ensure you set the CPU speed to 333 MHz in the Adrenaline settings.
for that platform. High-quality English versions, specifically the School Days HQ edition, were officially released for PC. For the PSP version (often titled School Days L×H school days iso psp english high quality