A: In class-compliant mode, yes . The USB MIDI standard works perfectly on Apple Silicon. However, the proprietary M-Audio kernel extension driver will not load on Apple Silicon Macs due to security architecture changes.
: If the keyboard behaves unexpectedly, perform a factory reset by holding down the +/- buttons while powering the unit on. maudio axiom pro 49 driver mac
This section addresses the core of your search. You have a modern Mac (with or without Apple Silicon M1/M2/M3) and you need the driver to work. Here are your three real-world options. A: In class-compliant mode, yes