For new development, consider moving to (cross-platform), but for maintaining existing Windows desktop apps, 4.8 is the stable, final destination.

Security and servicing .NET Framework 4.8 continues to receive security updates through Microsoft’s Windows servicing model. Key security considerations include:

If you glance at your "Turn Windows features on or off" panel on a modern Windows 10 64-bit machine, you’ll see a quiet entry sitting there:

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